Hi,

Last few weeks I was intensively involve in wire frame and prototype decision for my office project, We were spending lots of time to decide where should we place what, we are doing all this on paper, power point... Somehow we did that but I was not happy with our approach... I thought to find some good resource for how to do efficient wire-frame, and here is some output of my R&D.

- Paper/Pencil is efficient but its hard to re-use template, most of us have very bad drawing skills

- There are software like SmartDraw ,  Axure but all of these are paid 

- I found http://www.mockflow.com/ is very good but it also gives you only 4 pages site in free version, but its very good if you want to know what all you can do on web without installing any software and that's so easily.

- Finally I found one which is good and free both http://gomockingbird.com/mockingbird/ 

If you just want to draw some diagram and not interested in website prototype http://www.mxgraph.com  is also very good, It's java script based online tool.

My Reference:

• http://stackoverflow.com/questions/55363/best-tools-for-creating-website-wireframes
• http://garmahis.com/reviews/wireframe-tools/

- Everything here is based on my personal view, and nothing is related to my company.